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Home Products REAGENTS AND TOOLS Cell culture GMP level anti-human CD28 monoclonal antibody
GMP level anti-human CD16 monoclonal antibody
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Serium free freezing medium
Cryo-SFI Serum-Free Freezing Medium -100ml

GMP level anti-human CD28 monoclonal antibody

CD28 is a protein expressed by T cells that provides co-stimulatory signals required for T cell activation and survival. Stimulation of T cells by CD28, in addition to the T cell receptor (TCR), can also provide a potent signal for the production of various interleukins (especially IL-6).

CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2) proteins. CD80 expression is up-regulated in antigen presenting cells (APCs) upon activation of toll-like receptor ligands. CD86 expression on antigen-presenting cells is constitutive (expression is independent of environmental factors).

CD28 is the only B7 receptor constitutively expressed on Naïve T cells. Association of the TCR of Naïve T cells with the MHC: antigen complex without CD28:B7 interaction results in T cell anemia.

This product is a high-quality mouse monoclonal antibody preparation, including mouse anti-CD28 monoclonal antibody and carrier protein. The antibody recognizes the CD28 molecule, and the anti-CD28 antibody cooperates with the anti-CD3 antibody to stimulate T lymphocytes, and the proportion of CD8+CD25+ cells increases significantly, which can improve the tumor immunity of T cells.

*This product is for research use only.

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SKU: EN-C28-MAB Categories: Antibodies, Cell culture, Growth factors, Products
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Description

Anti-human CD28 antibody

T cell activating mAb

Cat. No. EN-C28MAB

Size:500µg

 

Product advantages

  1. High purity >95%
  2. High activity, high stability
  3. Low endotoxin <0.25EU/ ml
  4. Safe and contamination Free

Applications

Anti-CD28 monoclonal antibody is ideally used in cell therapy to activate T cell proliferation activation.

Product information

Immunogen Human CD28
Species Mouse
Molecular weight 150 KD
Form Liquid
Purification method Protein A affinity chromatography
Storage buffer 1×PB, 1.5mg/ml HSA, pH7.4
Storage condition 2-8℃
Validity 1 year

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      • GMP level antibodies
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